Featured Publications

Optimal Transport Scenario With Rotary Air Transport for Access to Endovascular Therapy Considering Patient Outcomes and Cost: A Modeling Study

Ashlee Wheaton*, Patrick T. Fok, Jessalyn K. Holodinsky, Peter Vanberkel, David Volders, and Noreen Kamal. "Optimal Transport Scenario With Rotary Air Transport for Access to Endovascular Therapy Considering Patient Outcomes and Cost: A Modeling Study." Frontiers in Neurology. 2021; 1y.

Abstract

Background: For an ischemic stroke patient whose onset occurs outside of the catchment area of a hospital that is capable of Endovascular Treatment (EVT) and whose stroke is suspected to be caused by a large vessel occlusion (LVO), a transportation dilemma exists. 

Discrete-Event Simulation to Model the Thrombolysis Process for Acute Ischemic Stroke Patients at Urban and Rural Hospitals

Bulmer, Tessa*; Volders, David; Blake, John; Kamal, Noreen. Discrete-event simulation to model the thrombolysis process for acute ischemic stroke patients at urban and rural hospitals. Frontiers in Neurology. 2021;12:article746404.

Abstract:

Background: Effective treatment with tissue plasminogen activator (tPA) critically relies on rapid treatment. Door-to-needle time (DNT) is a key measure of hospital efficiency linked to patient outcomes.

Selected Publications

Wheaton, A., For, P.T., Holodinsky, J.K., Vanberkel, P., Volders, D., Kamal, N. (2021). Optimal Transport Scenario with Rotary Air Transport for Access to Endovascular Therapy Considering Patient Outcomes and Cost: A Modelling Study. Frontiers in Neurology. 2021; 17:article769381. https://doi.org/10.3389/fneur.2021.768381 

Bulmer, T., Volders, D., Blake, J., Kamal, N. (2021). Discrete-event simulation to model the thrombolysis process for acute ischemic stroke patients at urban and rural hospitals. Frontiers in Neurology. 2021;12:article746404. https://doi.org/10.3389/fneur.2021.746404

Gillis, M., Saif, A., Murphy, M., Kamal, N. (2021). Effects of Various Policy Options on Covid-19 Cases in Nova Scotia Including Vaccination Rollout Schedule: A Modelling Study, MedRxIV, July. https://doi.org/10.1101/2021.07.28.21261219

Bulmer, T., Volders, D., & Kamal, N. (2021). Analysis of thrombolysis process for acute ischemic stroke in urban and rural hospitals in Nova Scotia Canada. Frontiers in neurology, 12. doi:https://doi.org/10.3389/fneur.2021.645228

Kamal, N., Jeerakathil, T., Stang, J., Liu, M., Rogers, E., Smith, E. E., ... & Hill, M. D. (2020). Provincial Door-to-Needle Improvement Initiative Results in Improved Patient Outcomes Across an Entire Population. Stroke, 51(8), 2339-2346. doi:https://doi.org/10.1161/STROKEAHA.120.029734

Holodinksy JK, Kamal N, Zerna C, Ospel JM, Zhu L, Wilson LT, Hill MD, and Goyal M. (2020). In what scenarios does a mobile stroke unit predict better patient outcomes? A modelling study. Stroke, 51(6), 1805-1812. doi:https://doi.org/10.1161/STROKEAHA.119.028474

Kamal N, Rogers E, Stang J, Mann B, Butcher KS, Rempel J, Jeerakathil T, Shuaib A, Goyal M, Menon BK, Demchuk AM, Hill MD. (2019). 1-Year Healthcare Utilization for Patients that Received Endovascular Treatment Compared to Control. Stroke, 50, 1883-1886. doi:https://doi.org/10.1161/STROKEAHA.119.024870

Kamal N, Shand E, Swanson R, Hill MD, Jeerakthil T, Imoukhuede O, Heinrichs I, Bakker J, Stoyberg C, Fowler L, Duckett S, Holsworth S, Mann B, Valaire S, Bestard J. (2019). Reducing door-to-needle times for acute ischemic stroke to a median of 30 minutes at a community hospital: a cohort study. Canadian Journal of Neurosciences, 46(1), 51-56. doi:https://doi.org/10.1017/cjn.2018.368

Holodinsky JK, Williamson TS, Demchuk AM, Zhao H, Zhu L, Francis MJ, Goyal M, Hill MD, Kamal N. (2018). Drip ‘n ship vs. mothership: modelling stroke patient transport for all suspected large vessel occlusion patients. JAMA Neurology, 75(12), 1477-1486. doi:https://doi.org/10.1001/jamaneurol.2018.2424

Kamal N, Wiggam MI, Holodinsky JK, Francis MJ*, Hopkins E, Frei D, Baxter B, Williams M, Nygren A, Goyal M, Hill MD, Jayaraman M. (2018). Geographic Modeling of Best Transport Options for Treatment of Acute Ischemic Stroke Patients: Applied to Influencing Health Policy in the USA and Northern Ireland. IISE Transactions on Healthcare Systems Engineering, 8(3), 220-226. doi:https://doi.org/10.1080/24725579.2018.1501623

Kamal N, Sheng S, Xian Y, Matsoualka R, Hill MD, Bhatt D, Saver J, Reeves M, Fonarow GC, Schwamm LH, and Smith EE. (2017). Delays in door-to-needle times and their impacton treatment time and outcomes in Get With the Guidelines Stroke. Stroke, 48, 946-954. doi:https://doi.org/10.1161/STROKEAHA.116.015712

Kamal N, Smith EE, Jeerakathil T, Hill MD. (2017). Thrombolysis: Improving door-to-needle times for ischemic stroke treatment, a narrative review. International Journal of Stroke, 13(3), 268–276. doi:https://doi.org/10.1177/1747493017743060